The expiry date indicated by the manufacturer on the label of the medicinal product indicating that until that date the medicine is the height of its potential and the manufacturer guarantees full safety and efficacy.
The expiry dates are required by law in the United States, and they began in 1979. They are approaching the expiry date which does not mean that the medicine has lost its potency and safety.
After the expiration date does not mean that your drug lost its potential, but it still has about 90% of its original potential and is no longer effective and does not become more harmful.
In general, the expiry date published by the manufacturer on average is 2-5years from the date of manufacture. The FDA allows the manufacturer to determine long-term extending from the expiration date.
The potency and efficacy of expired drugs or antibiotics
When the drug has been extracted from its source and stored in a suitable manufacturer condition in which it starts using and is manufactured it begins to lose its potential. The expiry date does not indicate that the drug has lost its potential and efficacy. But, it is only a guarantee symbol that is provided by the manufacturer for its 100% potential efficiency and.
Although, after an ongoing investigation it was found that after the expiration date of the drug and the conditions still stored optimal drug shows 90% potential and efficacy after 5 years past the expiration date.
A program called SLEP (shelf life extension program), which was carried out to reduce the cost of medicine to the army. They experimented on approximately 122 different drugs and found that 88% of these 122 drugs when stored in proper conditions have an average length of 66 months and a maximum length of 278 months.
Are expired antibiotics safe?
Expired medicines are believed to be toxic after their expiry date. However, there are virtually no reports on the toxicity of old products. Be that as it may, it is advisable not to take expired medicines without previous studies.
Medicines that should never be used after their expiry date
Drugs with a narrow therapeutic index and little decrease in pharmacological activity can lead to serious consequences for patients. Therefore, some of the medicines should not be taken after expiration. Be:
- Warfarin-narrow therapeutic index.
- Birth control / oral contraceptives.
- Nitroglycerin-loses power very quickly,
- Anticonvulsants-narrow therapeutic index,
- SR PROCAN – sustained-release procainamide,
- thyroid preparations,
- Insulin – losing power very quickly and stored in cold conditions,
- Dilantin, phenobarbital,
- Eye drops – this is very sensitive to any bacterial growth in solution once the preservatives are degraded.
What are the factors that negatively affect medicines
There is a long list of storage conditions of the drugs, depending on the type of drug, as well as different forms of dosing. The main contributing factor is:
These factors should be strictly followed for the correct storage of medicines. If you don’t go through the storage conditions thoroughly, the medicine may begin to degrade before its actual expiration date.
What factors should be considered before using an expired medicinal product
The five critical factors to be considered before using expired drugs are:
Type of Formulation: Today the drug is manufactured in different formulations that can be compressed, liquid, aerosol, etc. so that the stability of the formulation is essential considering the more unstable the formulation, the faster it degrades. Liquids are unstable comparable to tablets.
Storage Conditions: As it appears above storage conditions and if the medicine is maintained it remains more stable if left open it starts degrading.
The duration of time between initial manufacturing time and end use.
Type of Package and Packaging Closure System: Medicine should be packed in an appropriate let way says, For example, if the medicine is degraded by the light to be stored in an amber bottle.
The Appearance of The Medication: Do not take the tablet if it breaks and brittle, do not use if the tablet has lost its brightness, do not use tablet or capsule if it has become soft, emulsions and suspensions remain separate despite shaking over and over, injectable to appear discolored or form precipitates. Let’s take an easy example of distinguishing time aspirin is good to use or not, if aspirin is the smell is changed so it can make the smell stronger less the effectiveness and vice versa.
It is suggested to use expired or non-expired medicines
The law imposes on drugs and their effectiveness for the betterment of society. So your life depends on an outdated drug and is the maintenance medicine so always take the medication with 100% potency. But if your life does not depend on the medication and the problems are such as a headache, constipation, etc. you can try and see what happens next.
But her is a ”better safe, then I’m sorry.” Therefore, if you have better options use products with full efficiency and 100% potential.
I took expired antibiotics. Should I be worried?
Yes, if the patient is not able to substitute for the medication expired with the new and the medicine is not saving drugs or drugs that threaten the life and life is that there is no evidence of its dangerous effects after the expiration can take it also, if the medication is used for symptoms such as a cough, sneezing, headache, hay fever, mild cold pain, or any other normal symptoms.
No, if patients are from a bit of maintenance therapy and it is an essential life-saving medicine, then it is advised to discard the expired medicine properly, and you should get a new prescription. The conditions for which expired medicines are not to be used are heart disease, some serious infections, seizures, etc. one sees the doctor right away and gets proper advice and get a new prescription.
Some medicines that should never be used after expiration are:
birth control or oral contraceptives