How long does 30mg oxycodone stay in your system?


Oxycodone belongs to the class of drugs known as opioids (narcotic) analgesics. Oxycodone is an opioid anesthetic.

This medication is used to relieve pain (ranging from moderate to severe).

Oxycodone affects the human brain to change the sensitivity and reaction of your body to pain.


You should not use oxycodone if you have: severe asthma, breathing problems, obstruction in your stomach or intestines.

Its use is also not recommended if you are experiencing: allergies to any narcotic pain medications (for example, methadone, morphine, Vicodin, Lortab, and many others), or narcotic cough medicines containing codeine, hydrocodone or dihydrocodeine.

Remember that oxycodone can slow down or stop breathing, especially when you are just starting to use this medicine or whenever its dosage changes. You should not use oxycodone if you are already using these opioid drugs and are tolerant to it.

Never take large quantities of oxycodone or for longer than prescribed by your doctor.

Do not attempt to crush, crush, or open oxycodone tablets. Try to swallow it whole, to avoid the possibility of ingestion of a lethal dose of the drug.


Oxycodone can be addictive, even while taking it at regular doses. Therefore, take this drug exactly with the advice of your doctor.

Never share this drug with another person.

Abuse of narcotic pain medications can be addictive, overdose, or even death (this is especially dangerous for a child or another person using oxycodone without a prescription).

Tell your doctor if you are pregnant. Oxycodone can cause life-threatening withdrawal symptoms in a newborn if the mother takes this medicine during pregnancy. A child born dependent on a medical drug may need treatment for several weeks.

Oxycodone can pass into breast milk and thus harm the infant. You should not breastfeed while you are using this medication.Do not take oxycodone to a child without consulting a doctor.

In no case do not drink alcohol during the treatment with oxycodone, as this can cause dangerous side effects or lead to death.

Some drugs can interact with oxycodone and cause a condition called serotonin syndrome.

Make sure your doctor knows that you are also taking medication to treat depression, mental illness, Parkinson’s disease, migraine, severe infections, or to treat the prevention of nausea and vomiting.

To make sure that oxycodone is safe for you, tell your doctor if you have:


Any breathing problems or lung disease,

  • A history of head injury, brain tumors, or cramps,
  • History of drug abuse,
  • History of alcohol dependence,
  • Mental illness
  • Urination problems,
  • Liver or kidney disease
  • Addison’s disease or other disorders of the adrenal gland,
  • Problems with the gallbladder, pancreas, or thyroid,
  • And also if you use tranquilizers, such as Valium (diazepam, alprazolam, lorazepam, Ativan, Klonopin, X-wings, Xanax, etc.).


The onset of action: oral 10-15 minutes. Maximum effect: orally 30 – 60 minutes. 
Duration of action: oral 3-6 hours.


Stop taking all other narcotic pain relievers if you need to start taking oxycodone extended-release (oxycontin). Oxycodone should be taken strictly according to doctor’s prescription. Before use, read the instructions for this drug in detail. Oxycodone is recommended to be taken with food.

Drink more water to make it easier to swallow the pill and prevent choking.

Before taking oxycodone in a liquid form, remember that the dose measurement should be carried out using a special syringe or a special medical spoon (using a regular tablespoon will not allow you to measure out the dosage required for taking the drug).

Do not stop taking oxycodone suddenly after prolonged use, as you may experience unpleasant symptoms of withdrawal of medication from the body.

Never try to crush or break a pill, inhale powder, or add it to a liquid to inject into a vein, as this can be fatal. Talk to your doctor about how to safely stop using this drug.

Painkillers work best if they are used at the first sign of pain. If you wait until the pain has worsened the drug may not help.

If you have persistent pain (for example due to cancer), your doctor may recommend that you also take long-acting opioid drugs. In such a case, oxycodone can be used only when necessary (during sharp pains).

Other painkillers (for example, paracetamol, ibuprofen) can be taken with oxycodone.

Oxycodone can cause some side effects, especially if it is used regularly for a long period or in high doses (for example, anxiety, watery eyes, runny nose, nausea, sweating, muscle pain).

To avoid reactions to the withdrawal of the drug from the body, your doctor may gradually reduce the dosage of oxycodone.

Oxycodone may stop helping to suppress pain in cases of prolonged use.

Check with your doctor if this drug stops working on your pain.

Along with its benefits, oxycodone can rarely lead to addiction. This risk may increase if you have abused alcohol or drugs in the past.


Since, often, oxycodone is used when necessary, it is extremely difficult to skip the drug.

Skip the missed dose of oxycodone if it is time to take your next scheduled dose of medication. However, if you use the schedule while taking this drug, take the missed dose as soon as you remember it.

Do not take an extra amount of medication to make up for the missed oxycodone intake.


Call your doctor or call an ambulance in case of an overdose of oxycodone.

Overdosing with this drug can be fatal (especially in children).


Alcohol is not permitted during oxycodone use.

This drug may affect your thinking processes and reactions.

Do not drive a car and do not perform actions that may require you to increase concentration, reaction or attention – until you are sure that oxycodone will not cause you adverse reactions.

Grapefruit and grapefruit juice can interact with oxycodone and lead to undesirable side effects. Discuss the use of products with grapefruit content with your doctor.


Get emergency medical attention if you have any signs of an allergic reaction to oxycodone: urticaria, difficulty breathing, swelling of the face, lips, tongue or throat.

Like other narcotic drugs, oxycodone can slow breathing. A person’s death can occur if breathing becomes too weak.

Shallow breathing, slow heartbeat, Contact your doctor immediately if you have:

  1. Cold, sticky skin
  2. Convulsions
  3. Confusion of thought marked drowsiness,
  4. Infertility, menstrual periods,
  5. Impotence, sexual problems, loss of interest in sex,
  6. Low levels of cortisol in the blood – nausea, vomiting, loss of appetite, dizziness, fatigue or weakness.

Most often, oxycodone causes breathing problems in older people, seriously ill patients, exhausted, weakened, etc.

Seek immediate medical attention if you experience symptoms of serotonin syndrome such as agitation, hallucinations, fever, sweating, chills, fast heartbeat, muscle stiffness, twitching, loss of coordination, nausea, vomiting, or diarrhea.

Common side effects of taking oxycodone may include:


  1. Drowsiness, headache, dizziness, feeling tired,
  2. Stomach pain, nausea, vomiting, constipation, loss of appetite,
  3. Dry mouth
  4. Moderate itching


Oxycodone can be administered orally, intranasally, intravenously, intramuscularly, subcutaneously or rectally.

The standard adult dose for cancer pain relief includes:

Taking the drug in an amount of from 5 mg to 15 mg orally every 4-6 hours (in cases of severe pain).

The service, in this case, involves taking the drug in an amount of from 10 mg to 30 mg orally every 4 hours. Doses exceeding 30 mg should be used with great care.

The average total daily dose is approximately 105 mg per day.

The standard pediatric dose for children older than one year and weighing less than 50 kg: involves taking the drug in an amount of from 0.05 mg to 0.15 mg/kg every 4-6 hours as needed.

A standard pediatric dose for children older than 1 year and weighing more than 50 kg: provides for the drug in an amount of 5 mg orally every 6 hours (if necessary, the dose can be titrated to 10 mg orally every 3 to 4 hours).

This oxycodone dosage information is an introductory (standardly approved for certain types of pain).

Remember that oxycodone is an opioid analgesic drug and is taken to suppress pain, often in people with serious illnesses.

To determine the exact dosage of this drug, you must continuously be monitored by a doctor and follow all his instructions.

Only your doctor can advise you on the exact and necessary dosage of oxycodone.

The dosage of the drug being taken should be based on the results of your clinical studies and the response to treatment.

You do not need to self-medicate using oxycodone, as it can be dangerous to your health and life.


Narcotic (opioid) drugs can interact with many other medicines and cause dangerous side effects or even death. Be sure your doctor knows if you also use:

Other opioid pain medications,

Narcotic drugs that cause you drowsiness or slow breathing – sleeping pills, muscle relaxants, sedatives, tranquilizers or antipsychotics,

Drugs that affect serotonin levels in the body are drugs to treat depression, Parkinson’s disease, migraine, headache, serious infection, prevention of nausea or vomiting.

This list is not exhaustive.

Other drugs may interact with oxycodone, including prescription and non-prescription drugs, vitamins and herbal medicines.

Precautionary measures

1. Reduce the dose in elderly patients with hypovolemia, while using other drugs, sedatives.
2. The form of the drug may contain metabisulfite sodium, which can cause allergic reactions in susceptible individuals.
3. For nausea or vomiting, prescribe an antiemetic agent, for example, crucial (10 mg intravenously every 6 hours).
4. To prevent or treat constipation, increase the amount of fluid consumed, prescribe physical therapy and laxatives.
5. Tolerance is manifested by reducing the duration of action and the increasing need for a drug. In this case, add other narcotic analgesics, antidepressants, go to the reception of alternative opioids or add non-drug therapy.
6. Abrupt interruption of opiate use in patients with physical dependence may manifest symptoms of withdrawal syndrome. To avoid withdrawal, doses should be gradually reduced (for example, a decrease of 75% every 2 days).Further treatment of symptomatic withdrawal.
7. Combinations of a drug with other narcotic analgesics increase analgesia.
8. The appointment of regional blockades achieves enhancement of the analgesic effect.
9. Non-drug therapy includes transcutaneous electrical stimulation of the nerve and techniques such as thermal and cold applications, ultrasound, massage.
10. Patients should be warned that oxycodone can suppress their ability to solve complex problems that require concentration or physical coordination, such as driving a car or working in heavy industry.



Always check the medicine bottle to make sure you get the right pills (of the same brand and type) prescribed by your doctor.

Keep track of the amount of the drug in each new vial.

Oxycodone is a drug, and you should know if someone is misusing this drug or without a prescription.

Do not store oxycodone residues in tablet or liquid form.

Ask your pharmacist where you can dispose of this drug. If there is no such program in your city, flush unused tablets or liquid form of the drug into the toilet.

Discard unused oxycodone in liquid form if more than 90 days have passed.