How Long Does Advil Stay in Your System?

Advil is a medicinal, non-steroid, anti-inflammatory drug. Phenylpropionic acid derivative. It is used in the treatment of diseases associated with the musculoskeletal system, to reduce pain and all sorts of inflammation.

The composition of the drug

There is a medicine that quickly and permanently relieves from an exhausting headache, toothache, and pain in the joints.

We are talking about Advil which, in addition to the active substance – ibuprofen, includes the following excipients:

  • Sodium carbonate;
  • Sodium saccharinate;
  • Potassium carbonate;
  • Lemon acid;
  • Sucrose palmitate;
  • Magnesium stearate;
  • Monosodium citrate;
  • Flavors;
  • Hypromellose;
  • Monosodium citrate.

Operating principle

The active substance is ibuprofen, acts as follows:

  • As an analgesic (relieves);
  • Lowers the temperature;
  • Relieves inflammation;
  • Makes joints more mobile

Indications for use

According to the instructions for the use of Advil, it is used in the treatment of such intractable ailments, accompanied by pain and fever, such as:

  • Rheumatoid, gouty, psoriatic arthritis;
  • Inflammatory disorders of the musculoskeletal system;
  • Osteochondrosis;
  • Ankylosing spondylitis;
  • Pelvic inflammation;
  • Fever during infectious diseases.

Advil tablets successfully relieve the pain accompanying diseases such as:

  • Nostalgia;
  • Myalgia;
  • Migraine;
  • Toothache;
  • Arthritis;
  • Neuralgia;
  • Bursitis;
  • Neuralgic amyotrophy;
  • Tendovaginitis;
  • Crayfish;
  • Headache;
  • Arthritis;
  • Radiculitis.
Effectively relieves pain medicine Advil in the framework of postoperative and post-traumatic pain syndrome, which is accompanied by an inflammatory process.

Based on the instructions for use, Advil tablets are shown in the form of symptomatic therapy for the relief of pain and inflammatory processes. This remedy does not affect the development of diseases.

As the analgesic effect of ibuprofen?

Ibuprofen is an effective and relatively safe remedy discontinued. It has strong anti-inflammatory and antipyretic effect, which makes it well suited for the treatment of various pains.

Soothes pain of the head, teeth, muscles, joints, metrorrhagia, relieves symptoms of colds and flu-fever, etc.

Mechanism of action of Advil

Advil inhibits the biochemical activity of enzymes that synthesize tissue hormones-prostaglandins. First, it blocks the enzyme-constitutive cyclooxygenase (COX-1) – responsible for the production of prostaglandins, which perform important physiological functions.

Second, it also inhibits the so-called inductive cyclooxygenase (COX – 2) – responsible for the synthesis of painkillers proinflammatory prostaglandins, causing headache, muscle, etc.

How Long Does Advil Stay in Your System?

How Long Does Advil Stay in Your System?

Advil is rapidly absorbed from the gastrointestinal tract, partly in the stomach and, to a greater extent, in the small intestine. It is completely therapeutic and effective less than an hour after taking the pill.

The analgesic effect occurs after about 30 minutes. And lasts for 4-6 h. The Drug is completely excreted from the blood through 24 h after the last dose. The metabolite is excreted in the urine.

Forms of release

The most popular and popular form of release of this drug is considered to be pills, but there are Advil capsules, instructions for use for which will tell you how to take them.

For children under the age of 2 years, manufacturers have prepared drops, and for babies under 3 months – suspension and candles. Capsules are indicated for children under 12 years old.

How to use Advil?

Before you start taking Advil, it is prudent to consult with your doctor. The doctor will help to correctly calculate the dosage; it is important.

The dose is directly proportional to the form of the disease and only a qualified; the attending physician will be able to determine it.

According to the instructions for use, for arthritis and osteoarthritis, it is recommended to drink 400-600 mg of this drug within 24 hours.

If it is necessary to relieve pain during sprains and trauma, take 2.5 g per day, breaking this amount into several doses. As part of rheumatoid arthritis, 40 mg per kg of body weight is indicated for 24 hours. This number also needs to be broken down into several tricks.

Reception needs to be carried out after food because, taking tablets at the same time with food, slows down the rate of absorption of ibuprofen – the active substance Advila.

For infants aged 3 to 9 months, Advil candles are inserted into the anus – 1 candle 3 times every 24 hours. Children aged 2 months to 2 years – 1 candle 4 times in 24 hours.

The ointment should be used as a standard, lubricating the diseased areas of the body.


Before taking Advil, you should consider all contraindications, namely, whether:

  • Gastric and duodenal ulcers;
  • Diseases of the liver and kidneys;
  • Intestinal tract inflammation;
  • Internal bleeding;
  • Hypersensitivity to the components of Advilla;
  • Hepatic and renal failure;
  • Hyperkalemia.

Contraindications to the use of Advila are the third trimester of pregnancy and lactation. 

You can not drink it and those who recently suffered coronary artery bypass surgery.

You can take Advil, but with caution and under the supervision of a doctor with the following serious ailments:

  • Diseases of the digestive tract;
  • Cirrhosis;
  • High blood pressure;
  • Diabetes;
  • Peripheral artery disease;
  • Cerebrovascular diseases;
  • When bad habits: alcoholism and smoking;
  • With severe somatic diseases;
  • As part of the use of antiplatelet agents, selective inhibitors, oral agents.

Adverse reactions

When taking Advil tablets, the following side effects may occur:

  • Impaired digestion;
  • Nausea;
  • Diarrhea;
  • Erosive and ulcerative lesions of the stomach and intestines;
  • Long-term use of the drug can cause malfunctions of the kidneys and liver;
  • Insomnia;
  • Headache;
  • Dizziness;
  • Overexcitation;
  • Falling vision.
If you use Advil for an unreasonably long time, you can provoke anemia, thrombocytopenia, agranulocytosis.

The occurrence of allergies in the form of a rash on the skin, bronchospastic syndrome, aseptic meningitis.

Advil: analogous

There are the following analogues of Advil, which include the same active ingredient – ibuprofen:

  • Ibuprofen ;
  • Bren;
  • Amprofen;
  • Nurofen;
  • Ibuprom;
  • Faspik;
  • Advil Likvi-jels;
  • Pedea;
  • Brufen SR;
  • Artro Kam;
  • Burana;
  • Iprene;
  • Motrin;
  • Northwell;
  • Ibuprofen-verte;
  • Nebulin;
  • Solpaflex;
  • Reumafen

Cost of Advila

For a drug such as Advil, the price depends on the country of origin and the form of release. The cost of Russian-made ibuprofen analogues is from 50 rubles. 

German, Serbian, and English manufacturers of this drug provide Russian pharmacies Advil at a price of up to 200 rubles.

The high cost is typical for packages with a large number of tablets and capsules (40 or more). The volume of tubes with ointment also affects the final cost of this drug.