How Long Does Meloxicam Last?

Meloxicam has the following properties: reduces fever, produces an anesthetic effect, is used as an analgesic. Meloxicam is used for the symptomatic treatment of joint diseases. These include arthritis, osteoarthritis, and arthrosis.

Composition and release form

Different types of Meloxicam (Meloxicam C3, Meloxicam Sandoz, Pfizer, Prana, etc.) are the same drug.

From each other drugs differ only in names. All the listed medicines are available in regular dosage forms with the same dosages of the active ingredients.

Different types of the drug, analogous of Meloxicam, appeared because each manufacturer decided to register its drug as a separate trademark.

All types of drugs are available in several varieties:

  • Tablets prescribed for oral administration – 7.5 mg and 15 mg.
  • The solution intended for injection is 10 mg/ml.
  • Rectal suppositories – 15 mg.

The active ingredient is meloxicam in different doses. The drug itself is the name of the active substance.

How long does meloxicam last?

It depends on the medication and physiological issues of each. That’s why we work with time estimates.

To define the elimination time estimate, it is necessary to know the concept of terminal half-life.
Terminal half-life is the time when half the dose of a substance is deactivated and subsequently eliminated from the body.

Usually, it takes 4-5 terminal half-lives to consider that the substance has left the body.

The use of Meloxicam in the form of tablets

Meloxicam tablets must be taken orally during meals. They need to be swallowed whole; it is forbidden to break or chew.

According to the instructions, drink the drug Meloxicam requires a small amount of liquid. It will be enough to drink half a glass. Tablets can be applied before meals, but then the likelihood of side effects increases.

To reduce this risk to a minimum value, the use of Meloxicam during meals is recommended.

According to the instructions, the dose is selected individually for each patient. The selection takes into account the severity of the disease, the initial state, the body’s response to the therapy being conducted.

In the case of various diseases, the following dosages are prescribed:

  • In rheumatoid arthritis, meloxicam is prescribed 15 mg a day. If after treatment there is a persistent remission, the dosage is reduced to 7.5 mg;
  • Osteoarthritis is prescribed 7 milligrams once a day. If this dosage of the drug does not save from pain and does not prevent inflammation, then it increases to 15 milligrams;
  • When anklosiruyuschego spondyloarthritis doctor establishes the use of Meloxicam 15 milligrams per day;
  • For other inflammatory diseases, it is required to use 7 mg of Meloxicam medicine once a day.

According to the instructions, the maximum daily dosage of the drug is 15 mg. If the patient is over sixty-five years old and suffers from severe form of renal failure, the dosage is 7.5 mg.

Meloxicam in the form of injections

Injection solution Meloxicam, contained in ampoules, is ready for administration, it is not required to be diluted further. It is necessary to dial an injection into the syringe and inject intramuscularly.

The solution contains 10 mg/ml of the main substance. Since the ampoule contains 1.5 ml of a solution, there is 15 mg of the active ingredient in the ampoule. It should be taken into account when calculating the dosage.

Meloxicam Injection Solution is intended for intramuscular use. Intravenous administration is prohibited. It is due to the likelihood of allergic reactions and inflammation of the walls of veins with thrombosis.

It is recommended to inject the solution into the upper side square of the buttock since this particular part of the body contains a special muscle layer. In it, the solution after injection appears to be deposited. Therefore it will slowly flow into the blood. It is the cause of the long-term effects of drug Meloxicam.

To find this place for the injection, it is necessary to divide the buttock into four parts. The top square, located on the outside, is the most optimal site.

If it is prohibited to inject a shot in the area of the buttock, then it is required to inject a solution into a third of the thigh surface.

Before performing the injection, wipe the area thoroughly with a cotton swab dipped in an antiseptic solution. For this, you can use alcohol or Belasepte. Then it is necessary to pick up the solution in the syringe, turn it upside down with a needle, knock a little on the wall so that the bubbles are on the surface of the liquid.

Next you need to click on the piston to release a few drops of funds. Only after these procedures, you can enter the solution intramuscularly.

A dosage of the solution Meloxicam:

  • With osteoarthritis – 7.5 mg of the drug (half of one ampoule) once a day for five days. Then you need to use pills. If, after the first injection of the solution, no improvement is observed, the dosage increases to 15 mg.
  • Rheumatoid arthritis should be administered 15 mg once a day for five days.
  • In ankylosing spondylitis, 15 mg is administered once a day for five days.
  • For other inflammatory diseases, 7.5 milligrams should be administered once a day for seven days.

Patients who are over 65 years old need to administer 7.5 milligrams of the drug once a day for five days in various diseases. If a person suffers from renal failure, but creatinine clearance is 5 ml/min.

It is required to take the drug in a standard dosage. Reduce the dose needed if creatinine clearance is less than 5 ml/minute.

Indications, contraindications, side effects of the drug Meloxicam

Indications for taking Meloxicam

  • Rheumatoid arthritis;
  • Osteoarthritis;
  • Ankylosing spondylitis;
  • Other inflammatory diseases with a painful symptom.

The instructions indicate that the drug Meloxicam is intended for the treatment of these diseases, as it relieves pain, swelling and reduces the strength of the inflammatory process. Thanks to the use of Meloxicam, the movement in the affected joint is facilitated.

However, the drug cannot be considered mainly Meloxicam, as it relieves the symptoms, but does not affect the course of the disease.

For the disease not to progress over time, it is imperative that the therapy requires the inclusion of drugs that affect the causes of development.

Before taking the medication, it is necessary to carefully familiarize yourself with the possible side effects:

  1. Nervous system:
    • The emergence of vertigo;
    • Headache;
    • Consciousness is confused;
    • Mood swings;
    • The person is tormented by insomnia.
  2. Visual organs:
    • In the eyes of two;
    • Visual acuity worsens;
    • Conjunctivitis.
  3. Auditory organs:
    • Ringing in the ears;
    • Vertigo.
  4. Circulatory system:
    • Anemia;
    • The number of leukocytes in the blood decreases;
    • There are no basophils in the blood.
  5. Heart and vessels:
    • The heartbeat is increasing;
    • The pressure rises;
    • A rush of blood.
  6. Gastrointestinal tract:
    • Nausea with vomiting;
    • Belching after taking the remedy;
    • Pain in the abdomen;
    • Diarrhea, flatulence, etc .;
    • Gastritis;
    • Gastric and duodenal ulcer;
    • Hepatitis.
  7. Urinary system:
    • The emergence of difficulties associated with urination;
    • Acute urinary retention;
    • Nephritis;
    • Nephrotic syndrome;
    • Renal failure.
  8. Skin tissue:
    • The appearance of an itch;
    • Rash;
    • Dermatitis after taking the funds;
    • Necrolysis;
    • Erythema.
  9. Allergy:
    • Hives;
    • Rash;
    • Itching.
  10. Other side effects:
    • The appearance of cough;
    • Puffiness;
    • Asthma attacks;
    • In rare cases, fever.

Contraindications for using Meloxicam

  • Bleeding in the gastrointestinal tract, previously transferred.
  • Severe renal and hepatic failure.
  • Pregnancy;
  • Feeding a baby with breast milk.
  • Excess potassium in the blood.
  • Individual intolerance to the components that make up the tool.
  • Inflammatory diseases of the rectum.

The listed contraindications of Meloxicam relate to tablets, suppositories, and solution. However, injections have other contraindications, which also need to be familiar:

  • The development of asthma.
  • The simultaneous use of anticoagulants (for example, warfarin).
  • Kidney disease, progressing with time.
  • Heart failure.
  • Pain after shunting.

How long can meloxicam be used?

In full accordance with the instructions, the duration of the therapeutic course of Meloxicam is set individually for each patient. It depends on the severity of the disease and the persistence of the remission stage.

The course of application of Meloxicam for chronic diseases ranges from four to eight weeks, in acute conditions the duration is about 3 weeks.

The general rule, according to which the duration of use of the drug Meloxicam is determined, is an orientation to the patient’s well-being and the condition of his joints.

In other words, drug treatment will continue until the pain is relieved, and the joint does not recover. If the need arises, then Meloxicam courses can be repeated.

Use of Meloxicam during pregnancy

During pregnancy, as well as feeding the child, doctors do not recommend using Meloxicam. In high dosages, this drug causes a teratogenic effect, which can cause fetal deformity or death. Fetal death can occur if Meloxicam is used in a dose of more than five mg per pound of weight.

Despite the fact that the therapeutic dosage of Meloxicam for use is significantly lower than that which can cause deformity or fetal death, pregnant mothers should not use them, as it is not known definitively what this may lead to. In exceptional cases, a woman may need this medicine.

Apply Meloxicam it is possible only in the first two trimesters of pregnancy with the condition: the use of the application covers the potential risks to the fetus.

In the third trimester of pregnancy it is prohibited to use Meloxicam:

  • The drug can cause prolonged pregnancy;
  • The possibility of long delivery;
  • High likelihood of generic complications: the neck is not well revealed, etc.

Meloxicam: use for children

Meloxicam is prohibited from applying to patients less than fifteen years old. Otherwise, it may cause undesirable effects and many side effects of the application.

From the age of fifteen, the dosage of the medication is set independently by the attending physician. If possible, the drug is replaced by a similar drug, until the patient is eighteen years old.

Medicinal effects of Meloxicam

Meloxicam is ranked as a drug belonging to the category of NSAID drugs, and produces the following effects:

  • Relieves inflammation.
  • It has an analgesic effect.
  • Reduces fever in diseases and conditions arising from inflammatory processes.

These effects were achieved by slowing down the work of cyclohexanes. Cyclohexane is an enzyme that provides the formation of two active substances: leukotrienes and prostaglandins.

They are substances that ensure the onset and further maintenance of the inflammatory process in each organ, regardless of the cause. The cause may be an injury or infection that causes inflammation.

The use of Meloxicam stops the production of prostaglandins and leukotrienes. It causes the inflammation to subside naturally since there are no biological components necessary for support. The tool is an effective anti-inflammatory process.

Each inflammatory process (it does not matter the reason for its occurrence) is characterized by these five signs:

  • The appearance of redness;
  • Swelling;
  • Pain sensations;
  • Temperature;
  • Functions are impaired.

All these inherent characteristics are stopped by Meloxicam. This drug suppresses inflammation, eliminates pain and redness. The main distinguishing feature is the ability of a drug to act exclusively on one modification of cyclooxygenase called COX-2.

Compatibility Meloxicam with other drugs

Meloxicam steps in interaction with such drugs and causes the following consequences:

  • When taken with drugs NSAIDs (Paracetamol, Indomethacin, etc.) – increases the likelihood of tongue in the digestive tract.
  • With indirect anticoagulants (Warfarin, etc.), heparin and thrombolytic affinities (Alteplaza, Urokinase, etc.) – the likelihood of bleeding from the organs of the gastrointestinal tract increases.
  • With drugs that have a diuretic effect, the risk of developing renal failure increases, and pressure increases.
  • When taken with lithium salts, the lithium content in the blood rises, which is harmful due to its toxicity.
  • If at the same time used drugs designed to reduce pressure, their effect is reduced.

Similar drugs that have a similar spectrum of action with meloxicam:

  • Zornik in the form of tablets;
  • Analog Meloxicam – Piroxicam in the form of tablets and capsules for oral administration;
  • Tent kit in the form of capsules;
  • Analogue of the drug – Pyroxifer in the form of capsules.

How long can you take meloxicam?

At the forum, you recommend meloxicam as the gold standard for osteoarthritis. It is a selective drug that reduces its destructive effect on the gastrointestinal tract.

My mom has dysplastic coxarthrosis, and without meloxicam, it is worse for her to walk. We selected an optimal dosage of 7.5 mg/day once with food and a large amount of water.

However, a question still arises (which may have already been asked, but it is extremely difficult to find it by search because of the popularity of the word meloxicam on the forum) – how long can you take it? The annotation says nothing about this.

Every six months, we monitor the blood picture (although, for example, no one directs coagulability), platelets are normal, and the rest of the formula results.

What are the possible side reactions?

The drug is famous for its undesirable effects, which, according to statistical studies, develop in every third patient.

Among the side effects of Meloxicam should be highlighted:

  • nervous system disorders: headaches, dizziness, loss of attention, insomnia, problems with orientation in space, mood swings, and the like;
  • changes in the qualitative composition of the blood: anemia, thrombocytopenia;
  • disorders of the digestive tract: nausea, vomiting, abdominal pain, changes in stool;
  • a negative effect on the cardiovascular sphere, which is expressed by an increase in blood pressure and tachycardia;
  • skin allergies;
  • hearing and vision impairment;
  • asthma attacks;
  • local and general puffiness;
  • fever;
  • renal failure.